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Multiple Choice

Which pancreas hormone lowers blood glucose levels?

Insulin lowers blood glucose by helping cells take in glucose and by signaling the liver to store it. When blood sugar rises, pancreatic beta cells release insulin. It promotes the movement of GLUT4 glucose transporters to the cell membrane in muscle and fat tissue, boosting glucose uptake from the blood. In the liver, insulin stimulates glycogenesis (glucose to glycogen) and inhibits glycogenolysis and gluconeogenesis, reducing glucose production and release. The overall result is a drop in circulating glucose toward normal levels. Other pancreatic hormones don’t primarily lower glucose: glucagon raises glucose by stimulating hepatic glucose production; somatostatin mainly modulates the release of other hormones; gastrin affects digestion rather than blood glucose.

Insulin lowers blood glucose by helping cells take in glucose and by signaling the liver to store it. When blood sugar rises, pancreatic beta cells release insulin. It promotes the movement of GLUT4 glucose transporters to the cell membrane in muscle and fat tissue, boosting glucose uptake from the blood. In the liver, insulin stimulates glycogenesis (glucose to glycogen) and inhibits glycogenolysis and gluconeogenesis, reducing glucose production and release. The overall result is a drop in circulating glucose toward normal levels. Other pancreatic hormones don’t primarily lower glucose: glucagon raises glucose by stimulating hepatic glucose production; somatostatin mainly modulates the release of other hormones; gastrin affects digestion rather than blood glucose.