Megakaryocytes, which produce platelets, arise from which stem cell lineage?

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Multiple Choice

Megakaryocytes, which produce platelets, arise from which stem cell lineage?

Megakaryocytes, which make platelets, come from the myeloid branch of hematopoiesis. The hematopoietic stem cell splits into myeloid and lymphoid lines; megakaryocytes (and other cells like red blood cells, granulocytes, and monocytes) arise from the myeloid lineage. Platelets are produced by fragmentation of megakaryocytes, so their origin traces back to myeloid progenitors (the common myeloid/erythroid-megakaryocyte progenitor). Lymphoid stem cells give rise to lymphocytes, and neural crest cells are not involved in blood cell formation. Hence the correct lineage is the myeloid lineage.

Megakaryocytes, which make platelets, come from the myeloid branch of hematopoiesis. The hematopoietic stem cell splits into myeloid and lymphoid lines; megakaryocytes (and other cells like red blood cells, granulocytes, and monocytes) arise from the myeloid lineage. Platelets are produced by fragmentation of megakaryocytes, so their origin traces back to myeloid progenitors (the common myeloid/erythroid-megakaryocyte progenitor). Lymphoid stem cells give rise to lymphocytes, and neural crest cells are not involved in blood cell formation. Hence the correct lineage is the myeloid lineage.

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